KMID : 0043319940170050371
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Archives of Pharmacal Research 1994 Volume.17 No. 5 p.371 ~ p.374
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Antitumor and Immunomodulating Activities of the Polysaccharide Fractions from Artemisia selengensis and Artemisia iwayomogi
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Koo Kyoung-Ah
Kwak Jong-Hwan Lee Kang-Ro Zee Ok-Pyo Woo Eun-Rhan Park Ho-Kun Youn Hyun-Joo
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Abstract
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Effects of the polysaccharide fractions purified from Artemisia selengensis and Artemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell types in vivo and in vitro. Both ASP1 and AIP1 fractions also syuppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AIP1 fractios may have immunomodulating and antitumor activities.
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KEYWORD
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Artemisia selengensis, Artemisia iwayomogi, Macrophage, Lymphocyte, Immuno-modulating, Antitumor
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