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KMID : 0043319940170050371
Archives of Pharmacal Research
1994 Volume.17 No. 5 p.371 ~ p.374
Antitumor and Immunomodulating Activities of the Polysaccharide Fractions from Artemisia selengensis and Artemisia iwayomogi
Koo Kyoung-Ah

Kwak Jong-Hwan
Lee Kang-Ro
Zee Ok-Pyo
Woo Eun-Rhan
Park Ho-Kun
Youn Hyun-Joo
Abstract
Effects of the polysaccharide fractions purified from Artemisia selengensis and Artemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell types in vivo and in vitro. Both ASP1 and AIP1 fractions also syuppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AIP1 fractios may have immunomodulating and antitumor activities.
KEYWORD
Artemisia selengensis, Artemisia iwayomogi, Macrophage, Lymphocyte, Immuno-modulating, Antitumor
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